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Visceral fat and blood sugar levels

Visceral fat and blood sugar levels

The Difference Between Visceral Fat and Visceral fat and blood sugar levels Fat Visceral shgar hangs out in and levells your internal organs. Download references. Diabetes 48 : — Boden G, Chen X, Ruiz J, White JV, Rossetti L: Mechanisms of fatty acid-induced inhibition of glucose uptake. Download all slides. Maura Pettiti.

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Visceral Fat - What Is It \u0026 How to Get Rid of It Amalia Antioxidant-rich foods for liver detoxification, Yoshinori Miyazaki, Maura Pettiti, Masafumi Matsuda, Levles Mahankali, Sufar Santini, Ralph A. Visceral fat VF excess has faf associated suugar decreased peripheral insulin sensitivity Vicseral has been suggested to blopd to Visceral fat and blood sugar levels insulin resistance. However, the mechanisms Quick Metabolism Boost which VF impacts on hepatic glucose metabolism and the quantitative role of VF in glycemic control have not been investigated. In the present study 63 type 2 diabetic subjects age, 55 ± 1 yr; fasting plasma glucose, 5. In contrast, the relation of basal endogenous glucose output to VF was not statistically significant. We conclude that in patients with established type 2 diabetes, VF accumulation has a significant negative impact on glycemic control through a decrease in peripheral insulin sensitivity and an enhancement of gluconeogenesis.

Visceral fat and blood sugar levels -

However, this doesn't mean that slimmer people are unlikely to develop such conditions. Related: Will Running Solve My Pot Belly Problem? Insulin resistance is when the body produces insulin, but is unable to properly use it to control blood sugar.

Glucose sugar builds up in the blood, leading to diabetes. Carrying too much visceral fat poses many serious health problems. Studies have shown that there is a link between these excess fat cells and other chronic diseases such as heart disease, stroke, and even some cancers.

Visceral fat is also commonly known as belly fat. BMI body mass index is one way to determine if you are overweight and gauge your risk of type 2 diabetes.

To measure abdominal fat, it is better to use the waist circumference WC or the waist-hip ratio WHR. Measuring our waistlines is a relatively simple but good indicator of how much visceral fat we are carrying.

You are at higher risk of Type 2 diabetes if your waist circumference is: 90 cm Diet and exercise is the best way to reduce visceral fat. A well-balanced diet is not only helpful when it comes to weight loss.

It also helps reduce the health risks associated with unnecessary weight gain. Aerobic exercise, combined with a healthy diet, will help in shedding our visceral fat effectively.

We should also avoid or limit our alcohol consumption. Losing weight healthily is most effective in reducing visceral fat. But whether your waistline is 30, 35 or 40 inches, it is recommended that everyone should get at least minutes of moderate to vigorous activity each week, and continue to make wise and healthier eating choices to stay healthy and strong.

If you are between the ages of 18 and 39, find out your risk by taking the Diabetes Risk Assessment. Take the first step towards beating diabetes. My aim is to dissect these mechanisms using both human and animal studies.

A recent study finds that as many as 1 in 20 people may be able to reverse a type 2 diabetes diagnosis through lifestyle changes alone. Many people with diabetes eat low-fat cheese.

However, researchers have shown that both low-fat and regular cheese may be good for regulating insulin…. New research examines the link between the consumption of fructose-containing foods, sweetened beverages, and the risk of type 2 diabetes.

A study found that even 2 to 5 minutes of light walking right after eating may reduce the risk of type 2 diabetes. A review of the available evidence suggests that intermittent fasting can reduce or even remove the need for medication in people with type 2 diabetes.

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Medical News Today. Health Conditions Health Products Discover Tools Connect. Reversing diabetes: Visceral fat more important than overall weight.

By Timothy Huzar on September 30, — Fact checked by Jessica Beake, Ph. Share on Pinterest According to a small study, even people of moderate weight can reverse diabetes by losing visceral fat.

Type 2 diabetes. Weight loss without overweight? Preliminary study. Remission in two-thirds. Share this article. It was estimated that in there were million age 18—99 years people with diabetes worldwide.

These figures are expected to increase to million by , and it is estimated that almost half of all people In , approximately 5 million deaths worldwide in persons in the 20—99 years age range were attributed to diabetes [ 1 ].

Obesity, especially abdominal obesity, is a well-known underlying risk factor for the development of diabetes [ 2 ]. Visceral fat accumulation, which is a key feature of abdominal obesity, is in an upstream position in the pathogenesis and development of metabolic syndrome Mets with clustering of DM, dyslipidemia, and hypertension [ 2 ].

In particular, several epidemiologic studies have shown that excess visceral fat area VFA is a well-known risk factor for the development of DM and onset of cardiovascular disorders [ 2 , 3 ].

Therefore, measurement of visceral fat accumulation is important to assess subjects with high risk of DM and other cardiovascular disorders [ 2 , 3 , 4 ].

As for VFA cut-off values for Mets, there are several differences associated with age distribution, the number of study participants, degree of obesity, and ethnicity [ 2 , 3 , 4 , 5 ]. In Japan, visceral fat accumulation is generally recognized as a waist circumference WC of over 85 cm in men and over 90 cm in women, which correspond to a VFA of cm 2 in an abdominal computed tomography CT scan at the umbilical level [ 3 ].

However, the impact of subcutaneous fat accumulation remains controversial. Several previous reports indicated a protective effect for glucose metabolism [ 6 , 7 ].

In contrast, there is some evidence indicating a positive association between subcutaneous fat accumulation and adverse cardiometabolic risk factors, including diabetes [ 8 , 9 ].

There are differences between subcutaneous adipose tissue SCAT and visceral adipose tissue VAT present in the abdominal cavity [ 10 ], including anatomic, cellular, molecular, physiologic, clinical, and prognostic differences. Anatomically, VAT is present mainly in the mesentery and omentum and drains directly through the portal circulation to the liver.

Compared with SCAT, VAT is more cellular, vascular, and innervated, contains a larger number of inflammatory and immune cells, has less pre-adipocyte differentiating capacity, and has a greater percentage of large adipocytes [ 10 ]. The present study assessed the association between DM and VFA and subcutaneous fat area SFA estimated by CT scans in Japanese subjects.

This was a cross-sectional study that screened Japanese adults who participated in a voluntary health checkup conducted at Juntendo University Hospital from January to December , in Tokyo, Japan.

A total of subjects were excluded due to missing data, and 1 subject was excluded due to a duplicate case. Ultimately, participants were included in the present study men, ; women, Height, weight, body mass index BMI , and WC were measured with participants in the standing position.

BMI was calculated by dividing body weight kg by height squared m 2. Mean systolic blood pressure SBP and diastolic blood pressure DBP were calculated from the means of two upper-arm blood pressure measurements taken from participants who had been seated for at least 5 min.

Hemoglobin A1c HbA1c levels were determined by high-performance liquid chromatography using an automated analyzer. These characteristics can be used to assess lifestyle health, and strong associations have been found between healthy lifestyle practices and successful blood pressure control among patients with hypertension [ 13 ].

Healthy lifestyle items in the questionnaire included non-daily alcohol consumption, non-smoker status, exercise frequency of two or more times per week, BMI of From the self-administered questionnaire, we also collected information on present medical history of comorbidities, such as hypertension, DM, dyslipidemia, hyperuricemia, cardiovascular disease, and cerebrovascular disease.

If participants answered as having these comorbidities, we registered the participants with a medical history of these comorbidities present. Abdominal fat area, including VFA and SFA, was measured from CT scans taken at the level of the umbilicus while in the supine position and during late expiration according to Japanese guidelines for obesity treatment [ 14 ].

We manually traced the inner aspect of the whole trunk, muscular layer, and the abdominal wall. In the computerized method using commercial software designed for quantification of VFA and SFA Canon Medical Systems Corp. Abdominal VFA was defined as the fat area enclosed by the inner aspect of the abdominal wall, and SFA was defined as the fat area enclosed by the outer aspect of the abdominal wall [ 15 , 16 ].

The method is widely used and a previous study indicated that CT and magnetic-resonance imaging MRI may yield different absolute values of fat areas especially visceral fat but that the ranking of individuals on the basis of their fat areas will be similar by both methods [ 17 , 18 ].

Receiver operating characteristic ROC curve analysis was used to assess appropriate cut-off values of VFA and SFA, and we estimated the area under the curve AUC and measured the sensitivity and specificity for DM in both sexes.

All statistical analyses were performed using the Statistical Package for Social Sciences, version 22 SPSS Inc. The research protocol was reviewed and approved by the Ethics Committee of the Juntendo University Hospital no. The mean age SD of non-DM and DM was Participants with DM had significantly higher mean BMI, WC, and VFA compared to non-DM participants.

The mean SFA of DM participants was significantly higher than that of non-DM participants among women, whereas no statistically significant difference was observed among men. The proportions of hypertension and SBP were significantly higher in DM compared to non-DM participants in both sexes.

Mean HDL-C was significantly lower and TGs higher in DM compared to non-DM participants among both sexes. There was no association between SFA and DM. The appropriate VFA cut-off value, sensitivity, specificity, and AUC in men were The appropriate SFA cut-off value, sensitivity, specificity, and AUC in women were Analysis of visceral fat area receiver operating characteristic curve for diabetes mellitus in men.

AUC: area under the curve. Analysis of visceral fat area a and subcutaneous fat area b receiver operating characteristic curves for diabetes mellitus in women.

VFA was closely and positively associated with DM in both sexes, and appropriate estimated cut-off points might be SFA was also associated with DM only in women, suggesting a cut-off value of To the best of our knowledge, analyses of the association between DM and VFA and SFA are limited.

Visceral fat accumulation is widely regarded as a risk factor for cardiovascular diseases, including DM. Mets is a metabolic condition that predicts individuals who are likely to be affected by cardiovascular disorders via insulin resistance [ 3 ]. One major feature of Mets is visceral fat accumulation, which is closely related to insulin resistance.

Visceral fat accumulation is also known to be an independent risk factor for type 2 diabetes. A longitudinal study that determined the optimal cut-off value of VFA for predicting type 2 diabetes among 13, Koreans reported values of Another longitudinal survey that followed Japanese Americans for 10 years reported a baseline intra-abdominal fat area IFA of Also, an increase of 1 SD in IFA was associated with a 1.

These previous study results are closely similar to our results. Our results showed that SFA was significantly positively associated with DM in women, whereas no association was observed in men.

The role of subcutaneous fat in cardiovascular risk remains controversial. However, the association between SFA and newly diagnosed diabetes disappeared in men and was reversed in women OR 0. A study that surveyed participants from the Framingham Heart Study reported that multivariable-adjusted general linear regression analyses of SAT and VAT showed significant associations with blood glucose in both sexes [age-adjusted Pearson correlation coefficients; 0.

In addition, the magnitude of association between VAT and all risk factors was greater for women than men, and weaker sex differences were observed for SAT [ 8 ]. The Jackson Heart Study, which surveyed African Americans, reported that abdominal VAT and SAT were both associated with adverse cardiometabolic risk factors, including diabetes, and the effect size of VAT in women was larger than that of SAT [fasting plasma glucose, 5.

The possible mechanism of the association between diabetes and SAT as well as VAT is insulin resistance. To date, numerous studies have assessed the association between excess visceral fat accumulation and insulin resistance.

Regarding SAT, several previous surveys indicated a positive association between excess subcutaneous fat accumulation and insulin resistance.

Excess SAT accumulation may cause insulin resistance and contribute to glucose intolerance as well as VAT. Therefore, it is necessary to consider adiposity, including SAT and VAT, to better maintain body composition.

In regard to the impact of SAT, a sex difference was observed. There is little evidence available to explain the difference. Although the evidence is limited to explain the sex difference, it is possible that adiponectin may contribute. Further analyses are required to assess the sex difference.

Our study has several limitations. First, it was susceptible to selection bias, as the participants consisted of those who received voluntary medical check-ups at a single medical institution. As such, these participants may be inherently more aware of their health behaviors relative to the general population.

Ilan VicseralXiao Hui Ma Antioxidant-rich foods for liver detoxification, Xiao Man YangGil SkgarMichael W. ViwceralAnders H. BergPhillip SchererLuciano RossettiNir Barzilai; Removal of Visceral Fat Prevents Insulin Resistance and Glucose Intolerance of Aging : An Adipokine-Mediated Process? Diabetes 1 October ; 51 10 : — Age-dependent changes in insulin action and body fat distribution are risk factors for the development of type 2 diabetes. Visceral fat and blood sugar levels

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